Table 2 Target data and simulation results for a number of disturbances of the acid–base balance, single blood gas sample per disturbance
From: A white-box model for real-time simulation of acid–base balance in blood plasma
Normal | Respiratory acidosis | Hyperchloremia | Hypoalbuminemia | Hyperlactatemia | Metabolic acidosis | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Input variable | Units | ||||||||||||
[CO2]Σ | 26.4 | 22.2 | 12.9 | 32.9 | 16.9 | 17.6 | mmol/L | ||||||
Parameters | Units | ||||||||||||
[ALB] | 25 | 25 | 20 | 15 | 17 | 16 | mmol/L | ||||||
[PI] | 1.64 | 1.75 | 1.42 | 2.4 | 1.8 | 2.26 | mmol/L | ||||||
SIDapp | 35.9 | 29.7 | 25.5 | 42.1 | 28.1 | 38.6 | mmol/L | ||||||
[U−] | 0.0 | -0.4 | 6.0 | 0.8 | 4.6 | 14.1 | mmol/L | ||||||
Output variables | Target data | Sim. results | Target data | Sim. results | Target data | Sim. results | Target data | Sim. results | Target data | Sim. results | Target data | Sim. results | |
pH | 7.40 | 7.38 | 7.15 | 7.14 | 7.16 | 7.15 | 7.49 | 7.47 | 7.19 | 7.18 | 7.16 | 7.15 | - |
pCO2 | 5.60 | 5.36 | 8.00 | 7.67 | 4.50 | 4.33 | 5.70 | 5.54 | 5.60 | 5.36 | 6.20 | 5.95 | kPa |
[HCO3−] | 25.1 | 25.1 | 20.4 | 20.4 | 11.9 | 11.9 | 31.6 | 31.5 | 15.6 | 15.6 | 16.2 | 16.2 | mmol/L |